Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome
نویسندگان
چکیده
منابع مشابه
Changes in the composition and function of the gut microbiota in celiac disease
Evidence is supported the hypothesis that any changes in the composition and function of the gut microbiota play a fundamental role in a number of chronic inflammatory diseases including celiac disease (CD). In the last decade, several culture-independent methods have been developed to identify the components of the human microbiome. The study of microbiota based on nucleic acid analysis found ...
متن کاملUlcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota
BACKGROUND Previous studies suggest a link between gut microbiota and the development of ulcerative colitis (UC) and irritable bowel syndrome (IBS). Our aim was to investigate any quantitative differences in faecal bacterial compositions in UC and IBS patients compared to healthy controls, and to identify individual bacterial species that contribute to these differences. METHODS Faecal microb...
متن کاملDistinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis
AIM To characterize the gut bacterial microbiota of patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC). METHODS Stool samples were collected and relevant clinical data obtained from 106 study participants, 43 PSC patients with (n = 32) or without (n = 11) concomitant inflammatory bowel disease, 32 UC patients, and 31 healthy controls. The V3 and V4 regions of the 1...
متن کاملSURGICAL TREATMENT OF ULCERATIVE COLITIS
This is a preliminary report of 28 patients with ulcerative colitis who we surgically treated with "J" pouch endorectal pull-through operation from 1978 to 1996. All patients are continent with a median stool frequency of 4 times per day, no night soilage. low postoperative complications and one mortality due to pulmonary embolism.
متن کاملFecal microbiota in pouchitis and ulcerative colitis
AIM To investigate the changes in microbiota in feces of patients with ulcerative colitis (UC) and pouchitis using genomic technology. METHODS Fecal samples were obtained from UC patients with or without an ileal pouch-anal anastomosis (IPAA) procedure, as well as healthy controls. The touchdown polymerase chain reaction technique was used to amplify the whole V3 region of the 16S rRNA gene, ...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2020
ISSN: 1424-8247
DOI: 10.3390/ph13110346